Genetic Services - Anemia
PRENATAL DIAGNOSIS OF THALASSEMIA AND SICKLE CELL ANEMIA
Prenatal diagnosis and screening is the procedure of determining the health and condition of the unborn fetus with the main aim to detect born defects.
Before becoming parent, women at risk of having a baby with a genetically inherited disease of hemoglobin are advised to discuss the option available to diagnose the problem. Procedure will take few days to be done such as tissue sampling is done by chronic villi biopsy (8 to 10 weeks) or by amniocentesis (11 to 14 weeks) and diagnosis is done by DNA PCR method. It is the most sophisticated method in the world which gives appropriate results in 98-99% cases.
BANERJI ANEMIA RESEARCH FOUNDATION
The main objective of Anemia Research Foundation is to diagnose anemia in reproductive age group females from macro to molecular (DNA levels), so that proper reason can be found out and females can be treated specifically.
CHROMOSOMAL ANALYSIS (KARYOTYPING)
It is the process of preparing chromosomes for analysis that evaluates the number and structure of a person’s chromosomes in order to detect abnormalities. Each chromosome contains thousands of genes which are responsible for person’s inherited physical characteristics.
In case of repeated abortions, both the partner blood is checked for the chromosomal defects, by growing their blood cells artificially. However in case of earlier birth of Down syndrome (kind of disease with mental retardation) baby, further birth of similar baby can be prevented by analyzing the chromosomes of the earlier baby, their parents and if required of baby inside the uterus.
FISH (fluorescent in-situ hybridization )
FISH is one of the powerful molecular diagnostic techniques used to detect or confirm genes or chromosomes abnormalities. At the center, it is to be incorporated very soon and will give the diagnosis of various genetic disorders in few hours (compares to days in chromosomal analysis and DNA diagnosis).
The center is well equipped with all kinds of state of the art equipments for DNA based pathology like hepatitis, AIDS, malaria, tuberculosis etc. and treats various hormonal disease of the adolescents regularly like increased hair growth at unwanted places, irregular periods and obesity etc.